To kill creeping Charlie in the lawn, you’ll need a slightly stronger weed killer like Bonide Chickweed and Clover killer. It needs to be applied when night time temperatures are above 55 degrees F and daytime temperatures below 85 degrees (or it can harm the grass). This is usually mid to late May It needs to be applied when no rain or watering is expected for at least 48 hours after application since it is absorbed through the leaves. Since it is a vine, it will require regular monitoring and repeat applications will likely be necessary. Read and follow the directions on the product’s label